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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK7
All Species:
22.12
Human Site:
T110
Identified Species:
32.44
UniProt:
P50613
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50613
NP_001790.1
346
39038
T110
K
D
N
S
L
V
L
T
P
S
H
I
K
A
Y
Chimpanzee
Pan troglodytes
XP_518193
305
34323
K111
L
D
E
N
G
V
L
K
L
A
D
F
G
L
A
Rhesus Macaque
Macaca mulatta
XP_001092242
346
39008
T110
K
D
N
S
L
V
L
T
P
S
H
I
K
A
Y
Dog
Lupus familis
XP_850424
354
39795
T118
K
D
N
S
L
V
L
T
P
S
H
I
K
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q03147
346
38950
T110
K
D
N
S
L
V
L
T
P
S
H
I
K
A
Y
Rat
Rattus norvegicus
P51952
329
37122
L114
K
A
Y
M
L
M
T
L
Q
G
L
E
Y
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506541
324
36280
L112
Y
L
H
Q
H
W
I
L
H
R
D
L
K
P
N
Chicken
Gallus gallus
P13863
303
34670
Y110
S
R
V
K
S
Y
L
Y
Q
I
L
Q
G
I
V
Frog
Xenopus laevis
P20911
352
39672
T116
K
D
T
S
L
V
L
T
P
A
H
I
K
S
Y
Zebra Danio
Brachydanio rerio
A8WIP6
344
39006
H119
L
K
G
V
A
F
C
H
E
N
S
I
M
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511044
353
39655
T110
K
D
N
K
I
I
L
T
Q
A
N
I
K
A
Y
Honey Bee
Apis mellifera
XP_395800
321
36188
H114
L
H
Y
N
W
I
L
H
R
D
L
K
P
N
N
Nematode Worm
Caenorhab. elegans
P34556
332
38277
L120
G
K
D
E
Y
L
P
L
E
T
L
K
S
Y
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
I104
F
A
K
N
P
T
L
I
K
S
Y
L
Y
Q
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT0
391
44511
D110
N
I
F
L
S
P
A
D
I
K
S
Y
L
L
M
Baker's Yeast
Sacchar. cerevisiae
P06242
306
35228
M110
P
A
D
I
K
A
W
M
L
M
T
L
R
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
99.7
92.6
N.A.
95
91
N.A.
87.5
39.8
85.2
42.2
N.A.
65.7
63.8
39.3
N.A.
Protein Similarity:
100
88.1
99.7
95.4
N.A.
96.8
92.4
N.A.
88.7
56.3
90.3
59.5
N.A.
78.4
75.1
57.5
N.A.
P-Site Identity:
100
20
100
100
N.A.
100
13.3
N.A.
6.6
6.6
80
6.6
N.A.
60
6.6
0
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
26.6
N.A.
26.6
6.6
93.3
13.3
N.A.
86.6
20
20
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
49.1
41
N.A.
Protein Similarity:
N.A.
57.8
N.A.
65.2
60.6
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
7
7
7
0
0
19
0
0
0
32
7
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
44
13
0
0
0
0
7
0
7
13
0
0
0
0
% D
% Glu:
0
0
7
7
0
0
0
0
13
0
0
7
0
0
0
% E
% Phe:
7
0
7
0
0
7
0
0
0
0
0
7
0
0
0
% F
% Gly:
7
0
7
0
7
0
0
0
0
7
0
0
13
7
0
% G
% His:
0
7
7
0
7
0
0
13
7
0
32
0
0
7
7
% H
% Ile:
0
7
0
7
7
13
7
7
7
7
0
44
0
7
7
% I
% Lys:
44
13
7
13
7
0
0
7
7
7
0
13
44
0
0
% K
% Leu:
19
7
0
7
38
7
63
19
13
0
25
19
7
19
0
% L
% Met:
0
0
0
7
0
7
0
7
0
7
0
0
7
0
7
% M
% Asn:
7
0
32
19
0
0
0
0
0
7
7
0
0
7
13
% N
% Pro:
7
0
0
0
7
7
7
0
32
0
0
0
7
7
0
% P
% Gln:
0
0
0
7
0
0
0
0
19
0
0
7
0
7
0
% Q
% Arg:
0
7
0
0
0
0
0
0
7
7
0
0
7
0
7
% R
% Ser:
7
0
0
32
13
0
0
0
0
32
13
0
7
7
0
% S
% Thr:
0
0
7
0
0
7
7
38
0
7
7
0
0
0
7
% T
% Val:
0
0
7
7
0
38
0
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
7
7
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
13
0
7
7
0
7
0
0
7
7
13
7
38
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _